A life-altering betrayal leaves Donna Grace alone, unmarried, and pregnant. She's desperate to leave St. Louis, Missouri, and return to Santa Fe, New Mexico, where she grew up, and the only way back is by wagon train. The wagon master refuses to let a single woman drive a wagon without a male escort. Donna knows she can't trust men, but it seems she's going to have to partner with one if she wants to get back home.
Luke Russell failed to protect his fiancée. Because of his neglect, she was murdered. He vows to never leave another person to face dangers on their own and to never again open his heart to love. When he overhears Donna Grace's predicament he offers her a marriage of convenience that they will dissolve as soon they reach Santa Fe.
But the trail forces them to work together. The birth of Donna's baby unites them in a way they can't deny. Will the dangers and joys of the Santa Fe Trail break down the barriers these two have built around their hearts?