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Sarah is a burn-out. Her twenties have been wasted in a psychedelic haze. Now she wants to be sober, avoid temptation, so she joins a clinical trial to be sequestered away from the world.
Paranoia flows. Weird experiments are carried out on their waking and sleeping bodies. They realize the trial is changing them. Programming them. Installing false memories and removing emotions.
If they don't do something before their tenure ends, they might not be human when they leave.