It is a world like our own in every respect, save one. In the 1950s, random acts of possession begin to occur. Ordinary men, women, and children are the targets of entities that seem to spring from the depths of the collective unconscious, pop-cultural avatars some call demons.
As a boy, Del Pierce is possessed by the Hellion, an entity whose mischief-making can be deadly. With the help of Del's family and a caring psychiatrist, the demon is exorcised...or is it? Years later, following a car accident, the Hellion is back, trapped inside Del's head and clamoring to get out.
Del's quest for help leads him to Valis, an entity possessing the science fiction writer formerly known as Philip K. Dick; to Mother Mariette, a nun who inspires decidedly unchaste feelings; and to the Human League, a secret society devoted to the extermination of demons. All believe that Del holds the key to the plague of possession—and its solution. But for Del, the cure may be worse than the disease.